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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aefe9904f100606eb66ac765e5d829ddc1e279c6751d3fdbce9f2a185c3c2c71' 
  AND token = 'rVW8HlnePcuQGf4ZWYI7dzM1cx3Z5o9g07ToKpZFw9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}