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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd743802c4ed8999ff10d774cfcea2d8cc62e9ad4101c73f7e3d3cc16c674de83' 
  AND token = 'cDXkRIV8vDCR1Z1Ch/40GFIWrIl46q2znJ6kJOzSuJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}