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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a353762de8f35edf87c6f7c704f223105c76ce3cb19805616c94ec84b47557' 
  AND token = 'hgN2HIVWOVT8y5OocHJOKGx6MapOmC13RCzVUZMve98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}