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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c14269913fa4d8e70dca2d83d69077754cff6ecc3e167de49959e58d3eb2bb' 
  AND token = 'XHB0UjfNJV5eB5g4363b4sWA5BdE6g/QTGpRIJx6whc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}