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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f18a2bd613510f856de275693b51f2de1f23cc057d13527a939f1104911de5f6' 
  AND token = 'fWE0dR7BtxIDVOAaJMv3t8ye+W2C+aOGTE30LtFXfEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}