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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c2e44f4aabd534d01078ca09a40f90f032bfb82b2ee96c22860e6ae5d1bb2e2' 
  AND token = 'k9Ttj1kiwE1Z9omj6VvrVPJWgdDBESN/zHgSAWpZibo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}