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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e436d3a7b22dee974bff4c200b3763cc29fd6ce389ffd725e93efdb69263eaed' 
  AND token = '6dteLf+iker3omysyTUk2jA1Lp1vi80MwtcOkmo2LW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}