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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9244f20a1cef83da3eb96087048ee648ad614aee7d5b8230519cc2d7b592bc06' 
  AND token = '8Vf1p3Z80Dj/K6p5IrwgoPPKp0nplOUTRjPKlXeH4yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}