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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66363257b460ffdf308063113956c99c4dcc498232c069d1c774d78fc9c8af89' 
  AND token = 'TI//5d3H2hljb20xXRWLBFGfZVSF/u64tCMIlHU4sGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}