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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '742a57d580092de3b190df0288a6fe3116eee6918792f702db01e2b6557bdab6' 
  AND token = 'NYeHpYtN8PIf1jD9hvfclB+CsEa8ToN9qesPwxMsvLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}