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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff71b39cb4ec272c94d9e6d03da501a9e66057097edbe0f91d906067d03907c2' 
  AND token = 'n01yt1a3Lh9xEOclU8lnznpebM+nWqi9ZyyNnlKt2Zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}