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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a54e44e2a32b7bf301bc008f7db0fb72ecf51c14933252a46f8b9a4258546b9f' 
  AND token = 'uDkiFZHye44GVMXZueEvymC2aQzHk9LJMQBLB+wiSyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}