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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e528cdbd015022351eeb92280c0d11c3c35f80f1a6ccf50b8f39ec7110d50e5' 
  AND token = 'C8tMOudk8spdqOKphsya0widXoUkfhjMaBGV5KQjo+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}