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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf14d00ea63ab435ce4337a2a81ea848b6acc4a6c13dbdb035ad5a72142099a6' 
  AND token = 'iObPUQfz3bJ/LoxnmwQ1z3TbbcHfblkMSEKKSP1OMn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}