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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644dd7fde5982f3c4e0c46e1df5d7e9f45d723a11d94ec8932cff5638914d828' 
  AND token = 'L64c4S+TpxFiIRS7xjcO25CMMq4vVj0yR0X7+AofRnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}