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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de8e01af902524baf96c76459b482950c2119ca1e80db196c8d7d73180dbac8' 
  AND token = 'tDH8cLvPK2/TSAolmUs3nEzyyGoaeDeQCXpaKf2Q+tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}