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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57b0fcfb0d813aa15c28f35c3a200db5d49373b5f4b36127b3ddcce17c849a12' 
  AND token = '7pC1SqzGNK4nbaXPM73VTQhd8TykjJAk330kUt8axXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}