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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '748bb7e1b7ae3cb5c3cfb09f219efca5e6c7b76e33810563e170614c7825f4b5' 
  AND token = 'icmyN7pdvbyKVbcvLyrfO3n1tbykOPDyzUgtvwDkteU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}