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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '681b28acb7ea6fa2abed04763af3f333fe078c7834a253b7804d05f3f9a82a13' 
  AND token = '3oknTKwpfFvM8Mh1h11PUa/Gh2BYsZ1SoRRJmCyAv78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}