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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd478a0c369f20c58ad94d17288f3057f5a9c7a5830be9a80ea398329e5cdaaf4' 
  AND token = '89JNuv4i7lqaK/8YuLWfAlzAOtvMgR+mal/s+dxzKLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}