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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de8338f3b56aa3f88542fea0380d49296dd1aacd7df4c67265751fbb0117a226' 
  AND token = 'qNf4xNVqNo7OY8Wq8Z2DHXZB5mVS9fMfWVnLMFKcWuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}