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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a7c9cc8f1b2cc7fe3162a786dac0635423f1a6b3f8afc11a85388d022ecd498' 
  AND token = 'BB4P/VXibsMJ0DZWLs0vfE35Y903FvqV5Ts+CV/7K2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}