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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6818d0287e335e5bf352dd659c927492417dfd33e9c77a2690d3b9d5545b1fc8' 
  AND token = 'VH+13JtQHsXVWyJVjRRo/5Y+656qDqHBqSYd6m0q9Ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}