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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a510def44f8190b6885fbd8adccf7e99b562f13bb85d56c486965743829b756b' 
  AND token = 'D/fZT6u86rhs2hwtX3Y3JHB6N536aVHABTDETHcpIdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}