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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a5429426bb0abf1d81b3196c11dee05afca6191fad6aff6b0ab9162ee6bd9f' 
  AND token = 'hniigvRDmsHORGqzsB7OcNModN2MuZVa0N1/CQ1yE4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}