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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07521f2c4e64cca770a3af48a862ad680a0a0c7464da39348afd2fd8ce0833d5' 
  AND token = 'HKBJV+iY04QTi24eLkxRoxW8wE54U3KF7jx7k/OzDf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}