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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '844fa14b7e8f55f28586ceb0551f8ced808a58fb5d46f62d275e2e62089b8336' 
  AND token = 'dnLYsTVFFzckqL8+bPFANi/DOQtOFW2I5AHOsgZwvb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}