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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e4e62b17dcabec8ee7a688fd1e2c9e075694a67125d009f8f0f37f375088396' 
  AND token = 'fCNfA1RBsqB99INYb1zgSy3tMKuefWYVLxeHLfzIje4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}