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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ed1af04b10dff403f2470f3d16c0bd4bc0f408a08c5c7f5bb8c9b35328b587' 
  AND token = '/5CdFkfYaCCRqxBTAHN4+kYCrXrxzC+OdTuJ0j4XzPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}