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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3e399664cb21c300e9139d979e04942514cd6da660ac38fe37a969407b71e80' 
  AND token = '4QoVl79FNI8DTs2C0hv9pB4vMMK0puTf7DK2kFrtb28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}