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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da158bad754f51629dfcf5681f85f733d0b2513530e91208272ad8a7e3ec9e2d' 
  AND token = 'Rw5w9y88MTsTlfZs3tQbFLolvSP/TKNUBLJwOoiJpbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}