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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '441d30cccab74275b7082d542f1425a56155bd7cc29b4ed16809da0aba08629c' 
  AND token = 'GBR0OfORpb3TwixlGn+VW6Je42j4sY682nGdBxg1fmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}