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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '506033b2d75729f6d27a77285b3b62b0e338fe259b4968169031766cb4de9423' 
  AND token = '4KcG2QDD6LJKfHnPAosrO/ci+HM6JwNqidV6RYl2mCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}