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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '592228aaf5fe92dd0a92d7bd12e6f87c66ede702a7473e30c360ff5b6d0b1a88' 
  AND token = '6eKyW0z0E27hDVbsV1RgWpVUIVxZBD4NJsIB/8avHk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}