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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c1b40aa4aee64323820f49ffb348ec217b6385569ca6ea855036fd751cbebd2' 
  AND token = 'rcCqhgtLbDsHe8cimxXL3f+ViZE5aKHlNNyYVlL4WtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}