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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a8b037e2091e4011d541617310428084779c35ac8bde3022332712c8399a189' 
  AND token = 'bIq+TWgjhis67RujxThJCGPrafrEfTA90++g/p0VMAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}