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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea066cc1772dca357a2fc189f2ed6546facc40087665db4087b30bd16599fa7b' 
  AND token = 'ypxdJfWsAMqXrjyeWuiTB05B+wddD5dwVRwmYfe4cEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}