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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a021a70ff0bda29f23ccc78c0e15725c8cb000e3b4dc18ad1a2fb20e65cdda45' 
  AND token = 'oKjCb+gmd7kIcIus2t/xFOGmQqDSE/xOVDHFqvsNJMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}