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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca0a68338bfaba6c66c3c50947f2aba830a17567c193db47ce763722f23bf449' 
  AND token = 'AWGGYSuxl+vIt1ca1cnX/XpUpidJk4ZqvGXsvgYk488=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}