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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cd499bd013453a16567834098b95ada55b872dcb82c43b793b1a941be4aa242' 
  AND token = 'poqJsNBuwWstEkmsSWEra9AAN1fOdzmA+6rH4d0b9/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}