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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68b1c2aefab18503907e84f08f2b5ceb8ef875398bc5f00a080c59358e4c06b0' 
  AND token = 'sYqYFsHri8l91Z0o7ipHk1Pcg9huBh0q4jLNpIFQ0KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}