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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76e8b6c431d8b673fc6eaa3ae9b37a0bf522fc2665029dae750653108a406678' 
  AND token = 'cdQ7L3zfjN8pHoRKgdfcX4gb0g+cvYR3jFUjDdfPvxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}