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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48dabf472ff293f2b0cd862e92938511efa496dcac4ebbff5b505b219bcc6c6d' 
  AND token = 'sQFTRPxdT3Ic5jg0ic0D/05kzBHSqPOd+gfw72z0dE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}