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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e1445b54b6e34be0f52932e2e7b452e7a62d59439fe6ba36a9df352996aff98' 
  AND token = 'zvRnx/LzYTN4b9Q9XGVnhRMah2ICiJuvMLVTQ0t3xQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}