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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6449a93a89076c9c50ed561c2dbd92170d342cba93c8b3ff435ed7757052a1' 
  AND token = 'JuApVSqii+39t6ulL6P2QwVNcACeg8VB1I0IIKayUUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}