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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a2058fec4a8a6ab6d6bab18b2e504d4126ab76fe3c509b5bb828e79edb2495f' 
  AND token = 'R1fvzOmB1r+4tffW42+k0p7x1wODXFyGKxeNpPmcue8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}