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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35a78183d10483d4f05f6e6f15a81652982de15e52f252f0b8c8f1e89ce5be21' 
  AND token = 'kAcMb+EnuKp1KXrDW+ZvrJijJcBzWpWq4rLNjj7Tnuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}