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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7039c9f9814105e259224a215408f731f73d53206470087a33e391267843c3b0' 
  AND token = '9lF0kX/jLjDUjtmhrU5wP61NxNMG8TFTU6gmmhUs+Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}