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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00ec8066b668170b906e8e501e9f8dafed0fe0fa446aa0ba73d73b29c0dfd5a0' 
  AND token = '+e7sOz0Lf4sP8r4fDoVncw2kd7RTGgBRJCiqEZuqXAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}