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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ce8a0022abaa393bd413718da2e0f9725171cc7ce3fb1c1a07cae2732abd949' 
  AND token = '1BWob7nv61tqkcm2kHoPMouFiCLRL0+Ifuc5M6HFbd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}